Orbiting binary black hole evolutions with a multipatch high order finite-difference approach

We present numerical simulations of orbiting black holes for around twelve cycles, using a high-order multipatch approach. Unlike some other approaches, the computational speed scales almost perfectly for thousands of processors. Multipatch methods are an alternative to AMR (adaptive mesh refinement), with benefits of simplicity and better scaling for improving the resolution in the wave zone. The results presented here pave the way for multipatch evolutions of black hole-neutron star and neutron star-neutron star binaries, where high resolution grids are needed to resolve details of the matter flow

Tailoring 3D modelling techniques for epigraphic texts restitution. Case studies in deteriorated roman inscriptions

Digital Image Modelling is becoming a standard approach in epigraphic studies, mostly expressed in the diffusion practice of research groups which want their materials being publicly accessible. However, there is an important lack of works which seek for the use of 3D tools to improve the epigraphic analysis and text reading. Therefore, this paper attempts to show the application of Photogrammetry Structure from Motion and Digital Image Modelling to 3D record and analyse inscriptions that are in poor state of preservation, aiming to resolve some text-restitution problems and contribute towards the definition of new methodologies in Roman epigraphy

Mode coupling of Schwarzschild perturbations: Ringdown frequencies

Within linearized perturbation theory, black holes decay to their final stationary state through the well-known spectrum of quasinormal modes. Here we numerically study whether nonlinearities change this picture. For that purpose we study the ringdown frequencies of gauge-invariant second-order gravitational perturbations induced by self-coupling of linearized perturbations of Schwarzschild black holes. We do so through high-accuracy simulations in the time domain of first and second-order Regge-Wheeler-Zerilli type equations, for a variety of initial data sets. We consider first-order even-parity $(\ell=2,m=\pm 2)$ perturbations and odd-parity $(\ell=2,m=0)$ ones, and all the multipoles that they generate through self-coupling. For all of them and all the initial data sets considered we find that ---in contrast to previous predictions in the literature--- the numerical decay frequencies of second-order perturbations are the same ones of linearized theory, and we explain the observed behavior. This would indicate, in particular, that when modeling or searching for ringdown gravitational waves, appropriately including the standard quasinormal modes already takes into account nonlinear effects

Combining Internet Monitoring Processes, Packaging and Isotopic Analyses to Determine The Market Structure: Example of Gamma Butyrolactone

The Internet is becoming more and more popular among drug users. The use of websites and forums to obtain illicit drugs and relevant information about the means of consumption is a growing phenomenon mainly for new synthetic drugs. Gamma Butyrolactone (GBL), a chemical precursor of Gamma Hydroxy Butyric acid (GHB), is used as a "club drug" and also in drug facilitated sexual assaults. Its market takes place mainly on the Internet through online websites but the structure of the market remains unknown. This research aims to combine digital, physical and chemical information to help understand the distribution routes and the structure of the GBL market. Based on an Internet monitoring process, thirty-nine websites selling GBL, mainly in the Netherlands, were detected between January 2010 and December 2011. Seventeen websites were categorized into six groups based on digital traces (e.g. IP addresses and contact information). In parallel, twenty-five bulk GBL specimens were purchased from sixteen websites for packaging comparisons and carbon isotopic measurements. Packaging information showed a high correlation with digital data confirming the links previously established whereas chemical information revealed undetected links and provided complementary information. Indeed, while digital and packaging data give relevant information about the retailers, the supply routes and the distribution close to the consumer, the carbon isotopic data provides upstream information about the production level and in particular the synthesis pathways and the chemical precursors. A three-level structured market has been thereby identified with a production level mainly located in China and in Germany, an online distribution level mainly hosted in the Netherlands and the customers who order on the Internet

The funnel model of firms’ R&D cooperation with universities

[Abstract]: This paper explores the determinants of firms’ attitudes towards R&D cooperation with research groups understanding university-industry cooperation as a sequential process. In so doing, we study the determinants of both firms’ interest in and decision to engage in cooperation agreements. We applied both probit models and regression models for count data on a sample of 375 firms from Spain, Portugal and France. Although most of these firms showed interest in collaborating with universities, actually only 10% of the firms ended up cooperating with them. Our findings firstly indicate that innovative firms tend to show a more proactive attitude towards R&D collaboration. Secondly, within the group of firms interested in R&D collaboration, the firms really involved are the independent or small firms and we also provide evidence that country factors affect firms’ attitudes to R&D cooperation with universities

Is university-industry collaboration biased by sex criteria?

[Abstract]: This paper studies the attitudes and decisions of research groups led by men or women towards the collaboration with firms in research and development joint projects. We worked with a sample of 420 research groups of eight regions of Spain, France and Portugal in a sequential process. First, we studied the interest of the research groups to collaborate and, then, if the final decision of collaborating with firms changed according to the sex criteria. The results show that women are worse positioned in the social networks of collaboration and commercialization with industry. Research groups led by men have around 10% higher probability of showing interest in R&D cooperation with firms. However, when men and women leaders of research groups have the same motivation to collaborate, they do not differ in their decision of collaborating. These results evidence different initial attitudes towards university-industry collaboration according to sex criteria

Reversible Control of DNA Binding with Cucurbit[8]uril-Induced Supramolecular 4,4′-Bipyridinium–Peptide Dimers

Financiado para publicación en acceso aberto: Universidade da Coruña/CISUGThe Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acs.bioconjchem.1c00063[Abstract] Many cellular processes in living organisms are regulated by complex regulatory networks, built from noncovalent interactions between relatively few proteins that perform their functions by switching between homo- and heterooligomeric assemblies or mono- and bivalent states. Herein, we demonstrate that the conjugation of a 4,4′-bipyridinium scaffold to the basic region of the GCN₄ bZip transcription factor can be exploited to control the dimerization of the conjugate by formation of a supramolecular complex with cucurbit[8]uril. Importantly, this supramolecular complex is able to specifically recognize its target dsDNA, and this binding can be reversibly switched by the application of external stimuli.We are thankful for the funding received from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No 851179), the Ministerio de Economía y Competitividad and Fondo Europeo de Desarrollo Regional (FEDER) (CTQ2016-75629-P), the Agencia Estatal de Investigación and FEDER (CTQ2017-89166-R and PID2019-105272GB-I00) and the Consellería de Educación, Universidade e Formación Profesional, Xunta de Galicia (ED431C 2018/39). P.N thanks the Ministerio de Ciencia, Innovación y Universidades for her PhD fellowship (FPU17/04357). E.P. thanks the UDC-Inditex InTalent Programme for her research contract and funding and the Xunta de Galicia for the Oportunius ProgrammeXunta de Galicia; ED431C 2018/39https://pubs.acs.org/doi/suppl/10.1021/acs.bioconjchem.1c00063/suppl_file/bc1c00063_si_001.pd

Mujeres: efecto palanca del empleo en las spin-offs universitarias

[Resumen] En las últimas décadas el número de spin-offs creadas en los sistemas universitarios se ha incrementado considerablemente. El objetivo de este trabajo es contrastar si la presencia de mujeres en el capital social de las spinoffs universitarias españolas ejerce algún efecto sobre su crecimiento. Adicionalmente se contrasta esta misma hipótesis en un grupo de empresas de control no originadas a partir de la investigación universitaria con el fin de identificar posibles diferencias en el efecto del factor mujer. n Europa dende finais do século XIX, analizamos tamén a situació